Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Employed in the treatment of numerous myeloma. Its synthesis or study is vital for making certain the purity and security with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-ten-one): A essential compound within the synthesis of imatinib, a drug that targets distinct types of cancer, including Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their study is important for optimizing the creation system and making certain significant purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilized to CAS NO.61259-48-1 treat breast cancer, and these intermediates are involved with its production.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the treatment method of breast most cancers. Numerous intermediates help in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in 17b)-7-(9-Bromononyl)-estra-1 the treatment method of colorectal most cancers and compact mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-9): This compound is involved in the synthesis of adamantane derivatives, which have various applications, like antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-four to control blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of various gluconic acid derivatives, which can be used in meals, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication employed to manage kind two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).